You are here

Project Publications

All publications of the ANTIVIRALS project are freely available (Open Access), either directly via the Publisher or via the university's repository.

  • ESR-01 and ESR-02: Rachel Ulferts, S. Matthijn de Boer, Lonneke van der Linden, Lisa Bauer, Hey Rhyoung Lyoo, Maria J. Maté, Julie Lichière, Bruno Canard, Daphne Lelieveld, Wienand Omta, David Egan, Bruno Coutard and Frank J. M. van Kuppeveld. Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C. 2016. Antimicrob Agents Chemother. 60(5):2627-38 (http://europepmc.org/articles/PMC4862474)
  • ESR-01: Cristina M. Dorobantu, Lucian Albulescu, Heyrhyoung Lyoo, Mirjam van Kampen, Raffaele De Francesco, Volker Lohmann, Christian Harak, Hilde M. van der Schaar, Jeroen R. P. M. Strating, Alexander E. Gorbalenya, and Frank J. M. van Kuppeveld. Mutations in Encephalomyocarditis Virus 3A Protein Uncouple the Dependency of Genome Replication on Host Factors Phosphatidylinositol 4-Kinase IIIα and Oxysterol-Binding Protein. 2016. mSphere. (http://msphere.asm.org/content/1/3/e00068-16)
  • ESR-01 and ESR-02: Bauer L, Lyoo H, van der Schaar HM, Strating JR, van Kuppeveld FJ. Direct-acting antivirals and host-targeting strategies to combat enterovirus infections. Curr Opin Virol. 2017 Jun;24:1-8. doi: 10.1016/j.coviro.2017.03.009. Review. (http://www.sciencedirect.com/science/article/pii/S1879625716301547?via%3...)
  • ESR-01: Melia CE, van der Schaar HM, Lyoo H, Limpens RWAL, Feng Q, Wahedi M, Overheul GJ, van Rij RP, Snijder EJ, Koster AJ, Bárcena M, van Kuppeveld FJM. Escaping Host Factor PI4KB Inhibition: Enterovirus Genomic RNA Replication in the Absence of Replication Organelles. Cell Rep. 2017 Oct 17;21(3):587-599. doi: 10.1016/j.celrep.2017.09.068. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656745/
  • ESR-01: Lyoo H, Dorobantu CM, van der Schaar HM, van Kuppeveld FJM Modulation of proteolytic polyprotein processing by coxsackievirus mutants resistant to inhibitors targeting phosphatidylinositol-4-kinase IIIβ or oxysterol binding protein. Antiviral Res. 2017 Nov;147:86-90. doi: 10.1016/j.antiviral.2017.10.006. Epub https://www.sciencedirect.com/science/article/pii/S0166354217305181?via%...
  • ESR-3: Albulescu IC, Kovacikova K, Tas A, Snijder EJ, van Hemert MJ. Suramin inhibits Zika virus replication by interfering with virus attachment and release of infectious particles. Antiviral Res. 2017 Jul;143:230-236. doi: 10.1016/j.antiviral.2017.04.016. (https://www.sciencedirect.com/science/article/pii/S0166354217300931?via%...)
  • ESR-3: Hwu JR, Gupta NK, Tsay SC, Huang WC, Albulescu IC, Kovacikova K, van Hemert MJ. Bis(benzofuran-thiazolidinone)s and bis(benzofuran-thiazinanone)s as inhibiting agents for chikungunya virus. Antiviral Res. 2017 Aug 19;146:96-101. doi: 10.1016/j.antiviral.2017.08.008 (https://www.sciencedirect.com/science/article/pii/S0166354217304564?via%...)
  • ESR-10: Ferron F, Subissi L, Silveira De Morais AT, Le NTT, Sevajol M, Gluais L, Decroly E, Vonrhein C, Bricogne G, Canard B, Imbert I. Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E162-E171. doi: 10.1073/pnas.1718806115 (http://www.pnas.org/content/115/2/E162.long)
  • ESR-11 - Tassini S, Sun L, Lanko K, Crespan E, Langron E, Falchi F, Kissova M, Armijos-Rivera JI, Delang L, Mirabelli C, Neyts J, Pieroni M, Cavalli A, Costantino G, Maga G, Vergani P, Leyssen P, Radi M. Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases. J Med Chem. 2017 ;60(4):1400-1416. doi: 10.1021/acs.jmedchem.6b01521. (https://lirias.kuleuven.be/handle/123456789/573971)
  • ESR-11: Lanko, K., Eggermont, K., Patel, A., Kaptein, S., Delang, L., Verfaillie, C. M., & Neyts, J. (2017). Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals. Antiviral Research, 145. https://doi.org/10.1016/j.antiviral.2017.07.010